Recombinant Burkholderia mallei (strain ATCC 23344) Guanine nucleotide exchange factor BopE from MyBioSource.com

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Recombinant Burkholderia mallei (strain ATCC 23344) Guanine nucleotide exchange factor BopE

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Description

Activator for both CDC42 and RAC1 by directly interacting with these Rho GTPases and acting as a guanine nucleotide exchange factor (GEF). This activation results in actin cytoskeleton rearrangements and stimulates membrane ruffling, thus promoting bacterial entry into non-phagocytic cells